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2025, Vol: 15, Issue: 1
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Case Report
Online Published: 10 Jul 2025
 


Cartilaginous metaplasia of thyroid nodule

Madeeha Mujeeb, Jasmeen Tabassum, Naushaba Tazeen, Idrees Akhter Afroze, Imtiyaz Ahmed Khan.


Abstract
Adenomatous goiter is the most common form of thyroid disease. Although degenerative changes like fibrosis, calcification, cystic changes and hemorrhagic tissue are commonly found, cartilaginous metaplasia is an unusual phenomenon in the thyroid gland. Heterotopic cartilage formation is a very rare finding in both neoplastic and non-neoplastic lesions. Only 2 cases have been reported so far. Here we present a case of a 65-year-old female who presented with a midline swelling in her neck for 2 months associated with difficulty in swallowing. The lymph nodes were not palpable and there were no pressure symptoms. Ultrasonography was suggestive of thyromegaly with large goiterous change in left lobe and isthmus of thyroid. Fine Needle Aspiration Cytology (FNAC) revealed Bethesda Category I lesion. The patient underwent left hemi-thyroidectomy. Microscopy revealed encapsulated lesions composed of variable-sized follicles filled with colloid. Cystic areas lined by benign follicular cells showing foci of cartilage were also observed. Consistent with diagnosis of adenomatoid goiter with cartilaginous metaplasia. This case shows a rare histopathological change in the thyroid nodular lesions.

Key words: Adenomatous goiter, Cartilage, Metaplasia, Thyroid


 
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How to Cite this Article
Pubmed Style

Mujeeb M, Tabassum J, Tazeen N, Afroze IA, Khan IA. Cartilaginous metaplasia of thyroid nodule. J Med Allied Sci. 2025; 15(1): 92-94. doi:10.5455/jmas.214579

Web Style

Mujeeb M, Tabassum J, Tazeen N, Afroze IA, Khan IA. Cartilaginous metaplasia of thyroid nodule. https://jmas.in/?mno=214579 [Access: July 12, 2025]. doi:10.5455/jmas.214579

AMA (American Medical Association) Style

Mujeeb M, Tabassum J, Tazeen N, Afroze IA, Khan IA. Cartilaginous metaplasia of thyroid nodule. J Med Allied Sci. 2025; 15(1): 92-94. doi:10.5455/jmas.214579


Vancouver/ICMJE Style

Mujeeb M, Tabassum J, Tazeen N, Afroze IA, Khan IA. Cartilaginous metaplasia of thyroid nodule. J Med Allied Sci. (2025), [cited July 12, 2025]; 15(1): 92-94. doi:10.5455/jmas.214579


Harvard Style

Mujeeb, M., Tabassum, . J., Tazeen, . N., Afroze, . I. A. & Khan, . I. A. (2025) Cartilaginous metaplasia of thyroid nodule. J Med Allied Sci, 15 (1), 92-94. doi:10.5455/jmas.214579


Turabian Style

Mujeeb, Madeeha, Jasmeen Tabassum, Naushaba Tazeen, Idrees Akhter Afroze, and Imtiyaz Ahmed Khan. 2025. Cartilaginous metaplasia of thyroid nodule. Journal of Medical and Allied Sciences, 15 (1), 92-94. doi:10.5455/jmas.214579


Chicago Style

Mujeeb, Madeeha, Jasmeen Tabassum, Naushaba Tazeen, Idrees Akhter Afroze, and Imtiyaz Ahmed Khan. "Cartilaginous metaplasia of thyroid nodule." Journal of Medical and Allied Sciences 15 (2025), 92-94. doi:10.5455/jmas.214579


MLA (The Modern Language Association) Style

Mujeeb, Madeeha, Jasmeen Tabassum, Naushaba Tazeen, Idrees Akhter Afroze, and Imtiyaz Ahmed Khan. "Cartilaginous metaplasia of thyroid nodule." Journal of Medical and Allied Sciences 15.1 (2025), 92-94. Print. doi:10.5455/jmas.214579


APA (American Psychological Association) Style

Mujeeb, M., Tabassum, . J., Tazeen, . N., Afroze, . I. A. & Khan, . I. A. (2025) Cartilaginous metaplasia of thyroid nodule. Journal of Medical and Allied Sciences, 15 (1), 92-94. doi:10.5455/jmas.214579


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