E-ISSN 2231-170X | ISSN 2231-1696
 

Original Article 


Neonatal acute kidney injury - how mortality is related to its stage and the common co-morbidity among expired? A hospital based study

Sumanta Laha, Krishnendu Karmakar, Bhaswati Ghoshal.

Abstract
Objective of our study was to find out the incidence of Acute Kidney Injury (AKI) in neonates with their immediate outcome, how stages of AKI is related to mortality and what are the common co–morbid conditions among AKI deaths. In this observational prospective study we included the newborns with features suggestive of AKI with exclusion criteria of major congenital anomaly and extreme prematurity. AKI was diagnosed and classified according to the KDIGO (Kidney Disease: Improving Global Outcome) guideline taking serum creatinine and urine output as determinant. Cases were followed up till discharge or death. Now we have figured out the incidence of AKI in different stages, its immediate outcome and what are the percentage of mortality within each stage. Among the AKI deaths, we sort out the associated co-morbid conditions like perinatal asphyxia, sepsis, shock, prematurity, etc. and analyzed all the results statistically. Out of total 1923 neonates admitted during the 18 months study period we found AKI in 119 neonates (6.18%). Among them 75(63.03%), 26(21.85%) and 18(15.12%) neonates were in KDIGO stage 1, 2 and 3 respectively. We were able to discharge 68 neonates, 30 expired and the rest were referred out or LAMA. When we compare mortality among different stage, we found that it was 9.33% in stage 1 and 38.46% and 72.22% in stage 2 and 3 respectively. Among the various co-morbid conditions present among the expired neonates, sepsis(13) and perinatal asphyxia(12) were the leading ones followed by prematurity(3)and PPHN(2). So the conclusion is, if we can identify AKI early then chance of survival is better as we have shown in our study that mortality increases with the advancement of AKI stage. Sepsis and asphyxia ware the two most common co-morbid conditions among AKI deaths in our study.

Key words: Acute Kidney Injury (AKI), Co-morbidity, Mortality, Neonate


 
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How to Cite this Article
Pubmed Style

Laha S, Karmakar K, Ghoshal B. Neonatal acute kidney injury - how mortality is related to its stage and the common co-morbidity among expired? A hospital based study. J Med Allied Sci. 2021; 11(1): 97-100. doi:10.5455/jmas.135312


Web Style

Laha S, Karmakar K, Ghoshal B. Neonatal acute kidney injury - how mortality is related to its stage and the common co-morbidity among expired? A hospital based study. https://jmas.in/?mno=135312 [Access: December 05, 2023]. doi:10.5455/jmas.135312


AMA (American Medical Association) Style

Laha S, Karmakar K, Ghoshal B. Neonatal acute kidney injury - how mortality is related to its stage and the common co-morbidity among expired? A hospital based study. J Med Allied Sci. 2021; 11(1): 97-100. doi:10.5455/jmas.135312



Vancouver/ICMJE Style

Laha S, Karmakar K, Ghoshal B. Neonatal acute kidney injury - how mortality is related to its stage and the common co-morbidity among expired? A hospital based study. J Med Allied Sci. (2021), [cited December 05, 2023]; 11(1): 97-100. doi:10.5455/jmas.135312



Harvard Style

Laha, S., Karmakar, . K. & Ghoshal, . B. (2021) Neonatal acute kidney injury - how mortality is related to its stage and the common co-morbidity among expired? A hospital based study. J Med Allied Sci, 11 (1), 97-100. doi:10.5455/jmas.135312



Turabian Style

Laha, Sumanta, Krishnendu Karmakar, and Bhaswati Ghoshal. 2021. Neonatal acute kidney injury - how mortality is related to its stage and the common co-morbidity among expired? A hospital based study. Journal of Medical and Allied Sciences, 11 (1), 97-100. doi:10.5455/jmas.135312



Chicago Style

Laha, Sumanta, Krishnendu Karmakar, and Bhaswati Ghoshal. "Neonatal acute kidney injury - how mortality is related to its stage and the common co-morbidity among expired? A hospital based study." Journal of Medical and Allied Sciences 11 (2021), 97-100. doi:10.5455/jmas.135312



MLA (The Modern Language Association) Style

Laha, Sumanta, Krishnendu Karmakar, and Bhaswati Ghoshal. "Neonatal acute kidney injury - how mortality is related to its stage and the common co-morbidity among expired? A hospital based study." Journal of Medical and Allied Sciences 11.1 (2021), 97-100. Print. doi:10.5455/jmas.135312



APA (American Psychological Association) Style

Laha, S., Karmakar, . K. & Ghoshal, . B. (2021) Neonatal acute kidney injury - how mortality is related to its stage and the common co-morbidity among expired? A hospital based study. Journal of Medical and Allied Sciences, 11 (1), 97-100. doi:10.5455/jmas.135312