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2025, Vol: 15, Issue: 2
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Original Article 


A correlation of urine albumin creatinine ratio and serum cystatin C levels as an early diagnostic marker for diabetic nephropathy

Kumari Pallavi, Chowdam Suvarna Devi, Munirathnam Anuswaru.


Abstract
Diabetic nephropathy (DN) is one of the major health issues associated with type 2 diabetes mellitus (T2DM). T2DM is a major risk factor for end-stage renal disease (ESRD) and chronic kidney disease. Blood urea, urine albumin, creatinine, and serum cystatin C are common markers for the diagnosis and progression of DN. Our aim was to compare the levels of serum Cystatin C and other renal parameters in patients with diabetes mellitus (DM) and DN which included 120 participants were recruited based on the inclusion and exclusion criteria; of these, 60 were suffering from type-2DM and the remaining 60 were from DN. After taking the case history, the blood and urine samples were collected and sent to the laboratory for estimation of FBS and PPBS, blood urea, serum creatinine, serum cystatin C, and urine albumin creatinine ratio. Every participant in this study had higher blood glucose levels than usual. When both groups were compared, patients with DN showed higher levels of blood urea, serum creatinine, serum cystatin C, and urine albumin creatinine ratio than those with DM. conclusion is that levels of blood urea, creatinine, serum cystatin C, and urine albumin creatinine ratio were found to be higher in patients with diabetic nephropathy as compared to DM patients. Similarly, a positive correlation was found between the urine albumin creatinine ratio and serum cystatin C levels, so it can be considered an early diagnostic marker for diabetic nephropathy.

Key words: Blood glucose, Diabetes mellitus, Diabetic nephropathy, Serum cystatin


 
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How to Cite this Article
Pubmed Style

Pallavi K, Devi CS, Anuswaru M. A correlation of urine albumin creatinine ratio and serum cystatin C levels as an early diagnostic marker for diabetic nephropathy. J Med Allied Sci. 2024; 14(2): 33-37. doi:10.5455/jmas.202967

Web Style

Pallavi K, Devi CS, Anuswaru M. A correlation of urine albumin creatinine ratio and serum cystatin C levels as an early diagnostic marker for diabetic nephropathy. https://jmas.in/?mno=202967 [Access: June 27, 2026]. doi:10.5455/jmas.202967

AMA (American Medical Association) Style

Pallavi K, Devi CS, Anuswaru M. A correlation of urine albumin creatinine ratio and serum cystatin C levels as an early diagnostic marker for diabetic nephropathy. J Med Allied Sci. 2024; 14(2): 33-37. doi:10.5455/jmas.202967


Vancouver/ICMJE Style

Pallavi K, Devi CS, Anuswaru M. A correlation of urine albumin creatinine ratio and serum cystatin C levels as an early diagnostic marker for diabetic nephropathy. J Med Allied Sci. (2024), [cited June 27, 2026]; 14(2): 33-37. doi:10.5455/jmas.202967


Harvard Style

Pallavi, K., Devi, . C. S. & Anuswaru, . M. (2024) A correlation of urine albumin creatinine ratio and serum cystatin C levels as an early diagnostic marker for diabetic nephropathy. J Med Allied Sci, 14 (2), 33-37. doi:10.5455/jmas.202967


Turabian Style

Pallavi, Kumari, Chowdam Suvarna Devi, and Munirathnam Anuswaru. 2024. A correlation of urine albumin creatinine ratio and serum cystatin C levels as an early diagnostic marker for diabetic nephropathy. Journal of Medical and Allied Sciences, 14 (2), 33-37. doi:10.5455/jmas.202967


Chicago Style

Pallavi, Kumari, Chowdam Suvarna Devi, and Munirathnam Anuswaru. "A correlation of urine albumin creatinine ratio and serum cystatin C levels as an early diagnostic marker for diabetic nephropathy." Journal of Medical and Allied Sciences 14 (2024), 33-37. doi:10.5455/jmas.202967


MLA (The Modern Language Association) Style

Pallavi, Kumari, Chowdam Suvarna Devi, and Munirathnam Anuswaru. "A correlation of urine albumin creatinine ratio and serum cystatin C levels as an early diagnostic marker for diabetic nephropathy." Journal of Medical and Allied Sciences 14.2 (2024), 33-37. Print. doi:10.5455/jmas.202967


APA (American Psychological Association) Style

Pallavi, K., Devi, . C. S. & Anuswaru, . M. (2024) A correlation of urine albumin creatinine ratio and serum cystatin C levels as an early diagnostic marker for diabetic nephropathy. Journal of Medical and Allied Sciences, 14 (2), 33-37. doi:10.5455/jmas.202967


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