E-ISSN 2231-170X | ISSN 2231-1696
 

Case Report
Online Published: 11 Jan 2025
 


Subacute thyroiditis presenting as pyrexia of unknown origin and subsequent prolonged hypothyroidism – report of a rare case

Yagnya Darshit Dalal, Devagna Pradipkumar Mehta, Nandan Mehul Shah, Asjad Raza Chitalwala, Rajkamal Chaudhari.


Abstract
Pyrexia of unknown origin (PUO) poses a great diagnostic challenge to the clinicians and could be caused by infection, inflammation, neoplasm or other miscellaneous conditions. Subacute thyroiditis (SAT) is an inflammatory, self-limiting condition and is a very rare cause of PUO. Usually, it presents with anterior neck pain, tender goiter, and rarely with cervical lymphadenopathy. Clinical features of thyrotoxicosis may not be overt. This condition has viral etiology. Painless SAT is rare and can present as PUO. We present a rare case of SAT in a middle-aged male without any neck pain or thyromegaly. Investigations showed low TSH, elevated T3 and T4, raised ESR and CRP. Thyroid antibodies were negative. USG findings were typical of SAT. Tc99 scan showed poor or no uptake. Patient was treated with NSAIDs, oral steroids and beta blockers. He eventually developed hypothyroidism and is on thyroid supplement. We aim to highlight that painless SAT can be a cause of unexplained fever and clinician should keep this possibility in mind even in absence of clinical features of thyrotoxicosis.

Key words: PUO, Radioisotope scan, Subacute thyroiditis, Thyroid dysfunction, Thyroid function test, Ultrasonography


 
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How to Cite this Article
Pubmed Style

Dalal YD, Mehta DP, Shah NM, Chitalwala AR, Chaudhari R. Subacute thyroiditis presenting as pyrexia of unknown origin and subsequent prolonged hypothyroidism – report of a rare case. J Med Allied Sci. 2024; 14(2): 72-75. doi:10.5455/jmas.209306


Web Style

Dalal YD, Mehta DP, Shah NM, Chitalwala AR, Chaudhari R. Subacute thyroiditis presenting as pyrexia of unknown origin and subsequent prolonged hypothyroidism – report of a rare case. https://jmas.in/?mno=209306 [Access: January 11, 2025]. doi:10.5455/jmas.209306


AMA (American Medical Association) Style

Dalal YD, Mehta DP, Shah NM, Chitalwala AR, Chaudhari R. Subacute thyroiditis presenting as pyrexia of unknown origin and subsequent prolonged hypothyroidism – report of a rare case. J Med Allied Sci. 2024; 14(2): 72-75. doi:10.5455/jmas.209306



Vancouver/ICMJE Style

Dalal YD, Mehta DP, Shah NM, Chitalwala AR, Chaudhari R. Subacute thyroiditis presenting as pyrexia of unknown origin and subsequent prolonged hypothyroidism – report of a rare case. J Med Allied Sci. (2024), [cited January 11, 2025]; 14(2): 72-75. doi:10.5455/jmas.209306



Harvard Style

Dalal, Y. D., Mehta, . D. P., Shah, . N. M., Chitalwala, . A. R. & Chaudhari, . R. (2024) Subacute thyroiditis presenting as pyrexia of unknown origin and subsequent prolonged hypothyroidism – report of a rare case. J Med Allied Sci, 14 (2), 72-75. doi:10.5455/jmas.209306



Turabian Style

Dalal, Yagnya Darshit, Devagna Pradipkumar Mehta, Nandan Mehul Shah, Asjad Raza Chitalwala, and Rajkamal Chaudhari. 2024. Subacute thyroiditis presenting as pyrexia of unknown origin and subsequent prolonged hypothyroidism – report of a rare case. Journal of Medical and Allied Sciences, 14 (2), 72-75. doi:10.5455/jmas.209306



Chicago Style

Dalal, Yagnya Darshit, Devagna Pradipkumar Mehta, Nandan Mehul Shah, Asjad Raza Chitalwala, and Rajkamal Chaudhari. "Subacute thyroiditis presenting as pyrexia of unknown origin and subsequent prolonged hypothyroidism – report of a rare case." Journal of Medical and Allied Sciences 14 (2024), 72-75. doi:10.5455/jmas.209306



MLA (The Modern Language Association) Style

Dalal, Yagnya Darshit, Devagna Pradipkumar Mehta, Nandan Mehul Shah, Asjad Raza Chitalwala, and Rajkamal Chaudhari. "Subacute thyroiditis presenting as pyrexia of unknown origin and subsequent prolonged hypothyroidism – report of a rare case." Journal of Medical and Allied Sciences 14.2 (2024), 72-75. Print. doi:10.5455/jmas.209306



APA (American Psychological Association) Style

Dalal, Y. D., Mehta, . D. P., Shah, . N. M., Chitalwala, . A. R. & Chaudhari, . R. (2024) Subacute thyroiditis presenting as pyrexia of unknown origin and subsequent prolonged hypothyroidism – report of a rare case. Journal of Medical and Allied Sciences, 14 (2), 72-75. doi:10.5455/jmas.209306