E-ISSN 2231-170X | ISSN 2231-1696
 

Case Report 


Schwannoma of the adrenal gland

Anunayi Jeshtadi, Neelima Govada, Shrinivas B. Somalwar, Soumya Nagulapally.

Abstract
Visceral schwannomas are extremely rare and are usually discovered incidentally on USG/CT-Scan. Primary schwannomas of the adrenal gland are extremely uncommon. It has been theorized that they originate from Schwann cells that insulate the nerve fibers innervating the adrenal medulla. Histopathological examination coupled with immunohistochemistry provides the definitive diagnosis. A 55 year old normotensive female presented with pain in the right loin since 5 months. Her renal parameters were normal. Contrast enhanced computed tomography of abdomen showed a well delineated 6.5 x 5cms mass at upper pole of her right kidney. 24-hour urinary metanephrine was slightly elevated (3.07mg/24hrs). A decline in Serum cortisol levels was observed following a dexamethasone suppression test (18.89nmol/l). Histopathological examination revealed a spindle cell tumor. Immunohistochemistry showed strong and diffuse positive staining for S-100 with negative expression for CD-117, desmin, CD-34, HMB-45, synaptophysin, chromogranin, cytokeratin, and SMA. Ki-67 index was 2%.A diagnosis of cellular schwannoma of adrenal gland was confirmed.

Key words: Adrenal gland, Immunohistochemistry, S-100, Schwannoma


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Anunayi Jeshtadi
Articles by Neelima Govada
Articles by Shrinivas B. Somalwar
Articles by Soumya Nagulapally
on Google
on Google Scholar

REFERENCES
1. Jakowski JD, Wakely PE, Jimenez RE. An uncommon type of adrenal incidentaloma: a case report of a schwannoma of the adrenal medulla with cytological, histological, and ultrastructural correlation. Ann Diagn Pathol. 2008; 12:356-361. [DOI via Crossref]    [Pubmed]   
2. Lau SK, Spagnolo DV, Weiss LM. Schwannoma of the adrenal gland: report of two cases. Am J Surg Pathol. 2006; 30(5):630-634. [DOI via Crossref]    [Pubmed]   
3. Woodruff JM KH, Louis DN, Scheithauer BW. Schwannoma. Lyon, France: IARC Press, 2000.
4. Korets R, Berkenblit R, Ghavamian R. Incidentally discovered adrenal schwannoma. JSLS. 2007; 11(1):113-115. [Pubmed]    [PMC Free Fulltext]   
5. Tˆarcoveanu E, Dimofte G, Bradea C, et al. Adrenal schwannoma. JSLS. 2009; 13(1):116-119.
6. Yaseen M and Mary GF. Adrenal schwannoma: A Rare type of adrenal incidentaloma. Arch Pathol Lab Med 2013; 137(7):1009-1014. [DOI via Crossref]    [Pubmed]   
7. Woodruff JM, Godwin TA, Erlandson RA, Susin M, Martini N. Cellular Schwannoma: a variety of Schwannoma sometimes mistaken for a malignant tumor. Am J Surg Pathol 1981; 5:733-744. [DOI via Crossref]    [Pubmed]   
8. Gazula S and Mammen KJ. Schwannoma with concomitant tuberculosis in the adrenal gland. Indian J Urol 2007; 23:469-470. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   

How to Cite this Article
Pubmed Style

Anunayi Jeshtadi, Neelima Govada, Shrinivas B. Somalwar, Soumya Nagulapally. Schwannoma of the adrenal gland. J Med Allied Sci. 2014; 4(2): 77-80.


Web Style

Anunayi Jeshtadi, Neelima Govada, Shrinivas B. Somalwar, Soumya Nagulapally. Schwannoma of the adrenal gland. https://jmas.in/?mno=211792 [Access: January 12, 2023].


AMA (American Medical Association) Style

Anunayi Jeshtadi, Neelima Govada, Shrinivas B. Somalwar, Soumya Nagulapally. Schwannoma of the adrenal gland. J Med Allied Sci. 2014; 4(2): 77-80.



Vancouver/ICMJE Style

Anunayi Jeshtadi, Neelima Govada, Shrinivas B. Somalwar, Soumya Nagulapally. Schwannoma of the adrenal gland. J Med Allied Sci. (2014), [cited January 12, 2023]; 4(2): 77-80.



Harvard Style

Anunayi Jeshtadi, Neelima Govada, Shrinivas B. Somalwar, Soumya Nagulapally (2014) Schwannoma of the adrenal gland. J Med Allied Sci, 4 (2), 77-80.



Turabian Style

Anunayi Jeshtadi, Neelima Govada, Shrinivas B. Somalwar, Soumya Nagulapally. 2014. Schwannoma of the adrenal gland. Journal of Medical and Allied Sciences, 4 (2), 77-80.



Chicago Style

Anunayi Jeshtadi, Neelima Govada, Shrinivas B. Somalwar, Soumya Nagulapally. "Schwannoma of the adrenal gland." Journal of Medical and Allied Sciences 4 (2014), 77-80.



MLA (The Modern Language Association) Style

Anunayi Jeshtadi, Neelima Govada, Shrinivas B. Somalwar, Soumya Nagulapally. "Schwannoma of the adrenal gland." Journal of Medical and Allied Sciences 4.2 (2014), 77-80. Print.



APA (American Psychological Association) Style

Anunayi Jeshtadi, Neelima Govada, Shrinivas B. Somalwar, Soumya Nagulapally (2014) Schwannoma of the adrenal gland. Journal of Medical and Allied Sciences, 4 (2), 77-80.