Clinico-laboratory profile and treatment outcome of persistent diarrhea in under 5-year children of a tertiary care hospital in North India

Hanshika Srivastava; Manisha Maurya; Shahid Akhtar Siddiqui; Nandita Mishra; Anubha Shrivastava

doi:10.5455/jmas.88304

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Original Article

J Med Allied Sci. 2022; 12(1): 8-13

doi: 10.5455/jmas.88304

Clinico-laboratory profile and treatment outcome of persistent diarrhea in under 5-year children of a tertiary care hospital in North India

Hanshika Srivastava, Manisha Maurya, Shahid Akhtar Siddiqui, Nandita Mishra, Anubha Shrivastava.

Abstract
Persistent diarrhea (PD) accounts for a third of all deaths due to diar-rhea in under 5 children. Its etiology and treatment are poorly under-stood. So, we aimed to study various host and environmental risk fac-tors, clinical profile and treatment outcome of PD in children below 5 years of age. 60 children having PD who came to our institute were studied. History taking, clinical examination and investigations were done. Relevant data was collected in form of socio-demographic pro-file, infant and young child feeding (IYCF) indices, anthropometry, in-fections, micronutrient deficiency and secondary lactose intolerance (SLI). The treatment protocol consisted of stepwise diet plan along with supportive measures. All patients were started with diet plan A (low lactose diet), which was prepared by cheap and locally available items. Those who did not respond, were shifted to diet plan B (lactose free diet) and then to diet plan C (monosaccharide-based diet). Successful outcome was defined as decrease in stool frequency along with ade-quate food intake and weight gain. The risk factors associated with PD were found to be age < 2 years, malnutrition, SLI, micronutrient defi-ciency and previous history of infections. Out of total children (n=60), severe acute malnutrition, prior history of diarrhea/pneumonia in past 2 months and anemia were found in 58.3%, 60% and 52% of the PD children respectively. Concomitant enteric and systemic infections were found in 30% and 28.3% of PD children. SLI was observed in 61% of cases and most of the children (75%) improved on diet A only. Proper rehydration, screening and treatment of infections and enteral nutrition-al rehabilitation (both macro and micronutrient) are critical in manage-ment of children with PD.

Key words: Child, Diarrhea diet, Infection, Lactose, Malnutrition

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Pubmed Style

Srivastava H, Maurya M, Siddiqui SA, Mishra N, Shrivastava A. Clinico-laboratory profile and treatment outcome of persistent diarrhea in under 5-year children of a tertiary care hospital in North India. J Med Allied Sci. Online First: 09 Jan, 2023. doi:10.5455/jmas.88304

Web Style

Srivastava H, Maurya M, Siddiqui SA, Mishra N, Shrivastava A. Clinico-laboratory profile and treatment outcome of persistent diarrhea in under 5-year children of a tertiary care hospital in North India. https://jmas.in/?mno=88304 [Access: January 11, 2023]. doi:10.5455/jmas.88304

AMA (American Medical Association) Style

Srivastava H, Maurya M, Siddiqui SA, Mishra N, Shrivastava A. Clinico-laboratory profile and treatment outcome of persistent diarrhea in under 5-year children of a tertiary care hospital in North India. J Med Allied Sci. Online First: 09 Jan, 2023. doi:10.5455/jmas.88304

Vancouver/ICMJE Style

Srivastava H, Maurya M, Siddiqui SA, Mishra N, Shrivastava A. Clinico-laboratory profile and treatment outcome of persistent diarrhea in under 5-year children of a tertiary care hospital in North India. J Med Allied Sci, [cited January 11, 2023]; Online First: 09 Jan, 2023. doi:10.5455/jmas.88304

Harvard Style

Srivastava, H., Maurya, . M., Siddiqui, . S. A., Mishra, . N. & Shrivastava, . A. (2022) Clinico-laboratory profile and treatment outcome of persistent diarrhea in under 5-year children of a tertiary care hospital in North India. J Med Allied Sci, Online First: 09 Jan, 2023. doi:10.5455/jmas.88304

Turabian Style

Srivastava, Hanshika, Manisha Maurya, Shahid Akhtar Siddiqui, Nandita Mishra, and Anubha Shrivastava. 2022. Clinico-laboratory profile and treatment outcome of persistent diarrhea in under 5-year children of a tertiary care hospital in North India. Journal of Medical and Allied Sciences, Online First: 09 Jan, 2023. doi:10.5455/jmas.88304

Chicago Style

Srivastava, Hanshika, Manisha Maurya, Shahid Akhtar Siddiqui, Nandita Mishra, and Anubha Shrivastava. "Clinico-laboratory profile and treatment outcome of persistent diarrhea in under 5-year children of a tertiary care hospital in North India." Journal of Medical and Allied Sciences Online First: 09 Jan, 2023. doi:10.5455/jmas.88304

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Srivastava, H., Maurya, . M., Siddiqui, . S. A., Mishra, . N. & Shrivastava, . A. (2022) Clinico-laboratory profile and treatment outcome of persistent diarrhea in under 5-year children of a tertiary care hospital in North India. Journal of Medical and Allied Sciences, Online First: 09 Jan, 2023. doi:10.5455/jmas.88304

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