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Original Article 


Clinico-laboratory profile and treatment outcome of persistent diarrhea in under 5-year children of a tertiary care hospital in North India

Hanshika Srivastava, Manisha Maurya, Shahid Akhtar Siddiqui, Nandita Mishra, Anubha Shrivastava.

Abstract
Persistent diarrhea (PD) accounts for a third of all deaths due to diar-rhea in under 5 children. Its etiology and treatment are poorly under-stood. So, we aimed to study various host and environmental risk fac-tors, clinical profile and treatment outcome of PD in children below 5 years of age. 60 children having PD who came to our institute were studied. History taking, clinical examination and investigations were done. Relevant data was collected in form of socio-demographic pro-file, infant and young child feeding (IYCF) indices, anthropometry, in-fections, micronutrient deficiency and secondary lactose intolerance (SLI). The treatment protocol consisted of stepwise diet plan along with supportive measures. All patients were started with diet plan A (low lactose diet), which was prepared by cheap and locally available items. Those who did not respond, were shifted to diet plan B (lactose free diet) and then to diet plan C (monosaccharide-based diet). Successful outcome was defined as decrease in stool frequency along with ade-quate food intake and weight gain. The risk factors associated with PD were found to be age < 2 years, malnutrition, SLI, micronutrient defi-ciency and previous history of infections. Out of total children (n=60), severe acute malnutrition, prior history of diarrhea/pneumonia in past 2 months and anemia were found in 58.3%, 60% and 52% of the PD children respectively. Concomitant enteric and systemic infections were found in 30% and 28.3% of PD children. SLI was observed in 61% of cases and most of the children (75%) improved on diet A only. Proper rehydration, screening and treatment of infections and enteral nutrition-al rehabilitation (both macro and micronutrient) are critical in manage-ment of children with PD.

Key words: Child, Diarrhea diet, Infection, Lactose, Malnutrition


 
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How to Cite this Article
Pubmed Style

Srivastava H, Maurya M, Siddiqui SA, Mishra N, Shrivastava A. Clinico-laboratory profile and treatment outcome of persistent diarrhea in under 5-year children of a tertiary care hospital in North India. J Med Allied Sci. 2022; 12(1): 8-13. doi:10.5455/jmas.88304

Web Style

Srivastava H, Maurya M, Siddiqui SA, Mishra N, Shrivastava A. Clinico-laboratory profile and treatment outcome of persistent diarrhea in under 5-year children of a tertiary care hospital in North India. https://jmas.in/?mno=88304 [Access: December 04, 2023]. doi:10.5455/jmas.88304

AMA (American Medical Association) Style

Srivastava H, Maurya M, Siddiqui SA, Mishra N, Shrivastava A. Clinico-laboratory profile and treatment outcome of persistent diarrhea in under 5-year children of a tertiary care hospital in North India. J Med Allied Sci. 2022; 12(1): 8-13. doi:10.5455/jmas.88304


Vancouver/ICMJE Style

Srivastava H, Maurya M, Siddiqui SA, Mishra N, Shrivastava A. Clinico-laboratory profile and treatment outcome of persistent diarrhea in under 5-year children of a tertiary care hospital in North India. J Med Allied Sci. (2022), [cited December 04, 2023]; 12(1): 8-13. doi:10.5455/jmas.88304


Harvard Style

Srivastava, H., Maurya, . M., Siddiqui, . S. A., Mishra, . N. & Shrivastava, . A. (2022) Clinico-laboratory profile and treatment outcome of persistent diarrhea in under 5-year children of a tertiary care hospital in North India. J Med Allied Sci, 12 (1), 8-13. doi:10.5455/jmas.88304


Turabian Style

Srivastava, Hanshika, Manisha Maurya, Shahid Akhtar Siddiqui, Nandita Mishra, and Anubha Shrivastava. 2022. Clinico-laboratory profile and treatment outcome of persistent diarrhea in under 5-year children of a tertiary care hospital in North India. Journal of Medical and Allied Sciences, 12 (1), 8-13. doi:10.5455/jmas.88304


Chicago Style

Srivastava, Hanshika, Manisha Maurya, Shahid Akhtar Siddiqui, Nandita Mishra, and Anubha Shrivastava. "Clinico-laboratory profile and treatment outcome of persistent diarrhea in under 5-year children of a tertiary care hospital in North India." Journal of Medical and Allied Sciences 12 (2022), 8-13. doi:10.5455/jmas.88304


MLA (The Modern Language Association) Style

Srivastava, Hanshika, Manisha Maurya, Shahid Akhtar Siddiqui, Nandita Mishra, and Anubha Shrivastava. "Clinico-laboratory profile and treatment outcome of persistent diarrhea in under 5-year children of a tertiary care hospital in North India." Journal of Medical and Allied Sciences 12.1 (2022), 8-13. Print. doi:10.5455/jmas.88304


APA (American Psychological Association) Style

Srivastava, H., Maurya, . M., Siddiqui, . S. A., Mishra, . N. & Shrivastava, . A. (2022) Clinico-laboratory profile and treatment outcome of persistent diarrhea in under 5-year children of a tertiary care hospital in North India. Journal of Medical and Allied Sciences, 12 (1), 8-13. doi:10.5455/jmas.88304


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