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Review Article
Online Published: 07 Dec 2015
 


Free radicals, oxidative stress and importance of antioxidants in human health

Amit Kunwar, K.I. Priyadarsini.


Abstract
Reactive oxygen species (ROS) is a collective term used for oxygen containing free radicals, depending on their reactivity and oxidizing ability. ROS participate in a variety of chemical reactions with biomolecules leading to a pathological condition known as oxidative stress. Antioxidants are employed to protect biomolecules from the damaging effects of such ROS. In the beginning, antioxidant research was mainly aimed at understanding free radical reactions of ROS with antioxidants employing biochemical assays and kinetic methods. Later on, studies began to be directed to monitor the ability of anti-oxidants to modulate cellular signaling proteins like receptors, secondary messengers, transcription factors, etc. Of late several studies have indicated that antioxidants can also have deleterious effects on human health depending on dosage and bio-availability. It is therefore, necessary to validate the utility of antioxidants in improvement of human health in order to take full advantage of their therapeutic potential.

Key words: Reactive oxygen species, Oxidative stress, Antioxidant supplementation


 
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Pubmed Style

Amit Kunwar, K.I. Priyadarsini. Free radicals, oxidative stress and importance of antioxidants in human health. J Med Allied Sci. 2011; 1(2): 53-60.

Web Style

Amit Kunwar, K.I. Priyadarsini. Free radicals, oxidative stress and importance of antioxidants in human health. https://jmas.in/?mno=210124 [Access: September 12, 2024].

AMA (American Medical Association) Style

Amit Kunwar, K.I. Priyadarsini. Free radicals, oxidative stress and importance of antioxidants in human health. J Med Allied Sci. 2011; 1(2): 53-60.


Vancouver/ICMJE Style

Amit Kunwar, K.I. Priyadarsini. Free radicals, oxidative stress and importance of antioxidants in human health. J Med Allied Sci. (2011), [cited September 12, 2024]; 1(2): 53-60.


Harvard Style

Amit Kunwar, K.I. Priyadarsini (2011) Free radicals, oxidative stress and importance of antioxidants in human health. J Med Allied Sci, 1 (2), 53-60.


Turabian Style

Amit Kunwar, K.I. Priyadarsini. 2011. Free radicals, oxidative stress and importance of antioxidants in human health. Journal of Medical and Allied Sciences, 1 (2), 53-60.


Chicago Style

Amit Kunwar, K.I. Priyadarsini. "Free radicals, oxidative stress and importance of antioxidants in human health." Journal of Medical and Allied Sciences 1 (2011), 53-60.


MLA (The Modern Language Association) Style

Amit Kunwar, K.I. Priyadarsini. "Free radicals, oxidative stress and importance of antioxidants in human health." Journal of Medical and Allied Sciences 1.2 (2011), 53-60. Print.


APA (American Psychological Association) Style

Amit Kunwar, K.I. Priyadarsini (2011) Free radicals, oxidative stress and importance of antioxidants in human health. Journal of Medical and Allied Sciences, 1 (2), 53-60.


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