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Case Report
Online Published: 26 Jan 2018
 


Vitamin B12 deficiency causing neurological syndrome with rare skin manifestation

Samreen Fathima, Tukaram Umesh.


Abstract
Vitamin B12 is an essential vitamin for metabolism of carbohydrates, protein and fat. It is also required for proper functioning of nervous system. Skin hyper pigmentation, hair changes, vitiligo and angular stomatitis are cutaneous manifestations of vitamin B12 deficiency. Hyper pigmentation in Indian patients as first presentation of this deficiency is rarely reported. Our case was a 39-year-old lady who has presented with selective dark hyperpigmentation of hands and feet with electrophysiological evidence of peripheral neuropathy and biochemically proven vitamin B12 deficiency. Skin manifestation was reversed with intramuscular vitamin B12 administration of 1000mcg for 6 weeks. This case emphasizes the importance of rare skin presentation of reversible condition. It also marks the necessity of understanding all aspects and presentations of vitamin B12. Role of nutritional aspects of a person and their importance to prevent neurological sequel is discussed.

Key words: Cutaneous manifestations, Neurological manifestations, Vitamin B12 deficiency


 
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Pubmed Style

Fathima S, Umesh T. Vitamin B12 deficiency causing neurological syndrome with rare skin manifestation. J Med Allied Sci. 2018; 8(1): 49-52. doi:10.5455/jmas.275238

Web Style

Fathima S, Umesh T. Vitamin B12 deficiency causing neurological syndrome with rare skin manifestation. https://jmas.in/?mno=275238 [Access: June 27, 2026]. doi:10.5455/jmas.275238

AMA (American Medical Association) Style

Fathima S, Umesh T. Vitamin B12 deficiency causing neurological syndrome with rare skin manifestation. J Med Allied Sci. 2018; 8(1): 49-52. doi:10.5455/jmas.275238


Vancouver/ICMJE Style

Fathima S, Umesh T. Vitamin B12 deficiency causing neurological syndrome with rare skin manifestation. J Med Allied Sci. (2018), [cited June 27, 2026]; 8(1): 49-52. doi:10.5455/jmas.275238


Harvard Style

Fathima, S. & Umesh, . T. (2018) Vitamin B12 deficiency causing neurological syndrome with rare skin manifestation. J Med Allied Sci, 8 (1), 49-52. doi:10.5455/jmas.275238


Turabian Style

Fathima, Samreen, and Tukaram Umesh. 2018. Vitamin B12 deficiency causing neurological syndrome with rare skin manifestation. Journal of Medical and Allied Sciences, 8 (1), 49-52. doi:10.5455/jmas.275238


Chicago Style

Fathima, Samreen, and Tukaram Umesh. "Vitamin B12 deficiency causing neurological syndrome with rare skin manifestation." Journal of Medical and Allied Sciences 8 (2018), 49-52. doi:10.5455/jmas.275238


MLA (The Modern Language Association) Style

Fathima, Samreen, and Tukaram Umesh. "Vitamin B12 deficiency causing neurological syndrome with rare skin manifestation." Journal of Medical and Allied Sciences 8.1 (2018), 49-52. Print. doi:10.5455/jmas.275238


APA (American Psychological Association) Style

Fathima, S. & Umesh, . T. (2018) Vitamin B12 deficiency causing neurological syndrome with rare skin manifestation. Journal of Medical and Allied Sciences, 8 (1), 49-52. doi:10.5455/jmas.275238


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