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Original Article
Online Published: 09 Sep 2019
 


Lower serum selenıum levels are assocıated wıth dıvertıcular dısease of the colon

tugrul kesicioglu, raziye turan, AHMET CUMHUR DULGER, SELAHATTİN VURAL, ARZU AYRALER.


Abstract
Selenium plays a pivotal in many immunological events and inflammatory processes. Diverticular disease of the colon (DDC) is one of the most frequent gastrointestinal diseases and causes higher costs on the health system and deterioated quality of life for patients. DDC ecompasses a wide range of gastrointestinal diseases ranging from asymptomatic diverticular disease to perforated acute diverticulitis and peritonitis. Till date, no information is available describing the serum selenium levels in patients with DDC. In this study we aimed to investigate whether serum selenium deficiency is related to DDC. We compared 30 patients who had DDC and 40 patients without DDC. Diagnosis of DDC was done by colonoscopic examination. CT of the abdomen was also used for confirmation of DDC. Selenium concentrations of serum were determined using plasma mass spectrometry. There was a statistically significant difference between groups in terms of serum selenium levels (p<0.005). Furthermore, decreased selenium levels were also associated with high leucocyte and neutrophil levels (p<0.005). In this study, we found a clear association between DDC and low selenium levels. In conclusion, selenium deficiency may have a major role for developing DDC. In the future, selenium supplementation could be a preventive aproach to reduce the burden of the DDC in the world.

Key words: Diverticuler disease of the colon, Selenium


 
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How to Cite this Article
Pubmed Style

kesicioglu t, turan r, DULGER AC, VURAL S, AYRALER A, . Lower serum selenıum levels are assocıated wıth dıvertıcular dısease of the colon. J Med Allied Sci. 2019; 9(2): 67-69. doi:10.5455/jmas.30318

Web Style

kesicioglu t, turan r, DULGER AC, VURAL S, AYRALER A, . Lower serum selenıum levels are assocıated wıth dıvertıcular dısease of the colon. https://jmas.in/?mno=30318 [Access: September 12, 2024]. doi:10.5455/jmas.30318

AMA (American Medical Association) Style

kesicioglu t, turan r, DULGER AC, VURAL S, AYRALER A, . Lower serum selenıum levels are assocıated wıth dıvertıcular dısease of the colon. J Med Allied Sci. 2019; 9(2): 67-69. doi:10.5455/jmas.30318


Vancouver/ICMJE Style

kesicioglu t, turan r, DULGER AC, VURAL S, AYRALER A, . Lower serum selenıum levels are assocıated wıth dıvertıcular dısease of the colon. J Med Allied Sci. (2019), [cited September 12, 2024]; 9(2): 67-69. doi:10.5455/jmas.30318


Harvard Style

kesicioglu, t., turan, r., DULGER, A. C., VURAL, S., AYRALER, A. & (2019) Lower serum selenıum levels are assocıated wıth dıvertıcular dısease of the colon. J Med Allied Sci, 9 (2), 67-69. doi:10.5455/jmas.30318


Turabian Style

kesicioglu, tugrul, raziye turan, AHMET CUMHUR DULGER, SELAHATTİN VURAL, ARZU AYRALER, and . 2019. Lower serum selenıum levels are assocıated wıth dıvertıcular dısease of the colon. Journal of Medical and Allied Sciences, 9 (2), 67-69. doi:10.5455/jmas.30318


Chicago Style

kesicioglu, tugrul, raziye turan, AHMET CUMHUR DULGER, SELAHATTİN VURAL, ARZU AYRALER, and . "Lower serum selenıum levels are assocıated wıth dıvertıcular dısease of the colon." Journal of Medical and Allied Sciences 9 (2019), 67-69. doi:10.5455/jmas.30318


MLA (The Modern Language Association) Style

kesicioglu, tugrul, raziye turan, AHMET CUMHUR DULGER, SELAHATTİN VURAL, ARZU AYRALER, and . "Lower serum selenıum levels are assocıated wıth dıvertıcular dısease of the colon." Journal of Medical and Allied Sciences 9.2 (2019), 67-69. Print. doi:10.5455/jmas.30318


APA (American Psychological Association) Style

kesicioglu, t., turan, r., DULGER, A. C., VURAL, S., AYRALER, A. & (2019) Lower serum selenıum levels are assocıated wıth dıvertıcular dısease of the colon. Journal of Medical and Allied Sciences, 9 (2), 67-69. doi:10.5455/jmas.30318


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