E-ISSN 2231-170X | ISSN 2231-1696
 
2021, Vol: 11, Issue: 2
11/2Current Issue Online FirstArchiveAims and ScopeAbstracting & IndexingMost Accessed ArticlesMost Downloaded ArticlesMost Cited Articles

Original Article 


Lipid profile of patients having non-alcoholic fatty liver disease as per ultrasound findings in north Indian population: A retrospective observational study

Abhijit Sen, Jitendra Kumar, Rajendra Prasad Misra, Muneer Uddin, P. C. Shukla.

Abstract
A hospital-based cross-sectional study was conducted to assess the lipid profile and body mass index (BMI) of the patients suffering from non-alcoholic fatty liver disease (NAFLD) in north Indian population. A total of 385 ultrasound proven NAFLD patients were included in the study. The demographic and lipid profile such as total cholesterol, serum triglycerides, serum HDL, serum LDL and serum VLDL were recorded. The mean age of the patients was 46.65±15.06 years. The mean BMI was 29.50±3.34. Increased lipid levels were observed. Majority of the patients were in Grade 0 (83.4%) followed by Grade I (11.7%), Grade II (3.1%) and Grade III (1.8%). The total cholesterol level was significantly (p<0.0001) higher among fatty liver Grade III (300.57±167.98) than Grade 0 (128.79±70.42), Grade I (181.89±55.22) and Grade II (221.09±97.73). Similarly, triglyceride level was also higher among the fatty liver Grade III (431.61±48.76) patients as compared to Grade 0 (121.60±61.11), Grade I (203.81±33.55) and Grade II (278.34±70.41) and the differences were statistically significant (p<0.0001). Similar observations were found for HDL and VLDL. However, LDL was almost similar among all the grades of the pa-tients. There was no significant difference in the lipid levels with respect to gender. No association was found between fatty liver grade and sex and BMI. We found abnormal level of lipid profile amongst patients with fatty liver. A case-control study is recommended to find better understanding of lipid levels among NAFLD subjects.

Key words: BMI, Lipid level, NAFLD


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Abhijit Sen
Articles by Jitendra Kumar
Articles by Rajendra Prasad Misra
Articles by Muneer Uddin
Articles by P. C. Shukla
on Google
on Google Scholar

REFERENCES
1. Tominaga K, Kurata JH, Chen YK, et al. Prevalence of fatty liver in Japanese children and relationship to obesity. An epidemiological ultrasonographic survey. Dig Dis Sci. 1995; 40(9):2002-2009. [DOI via Crossref]    [Pubmed]   
2. Franzese A, Vajro P, Argenziano A, et al. Liver involve-ment in obese children. Ultrasonography and liver enzyme levels at diagnosis and during follow-up in an Italian population. Dig Dis Sci. 1997; 42(7):1428-1432. [DOI via Crossref]    [Pubmed]   
3. Feldstein AE, Youssef M, Freese DK, et al. Nonalcoholic fatty liver disease in children: a follow-up study for up to 16 years. Gastroenterol 2003; 124:701. [DOI via Crossref]   
4. Angulo P. Nonalcoholic fatty liver disease. N Engl J Med. 2002; 346:1221-1231. [DOI via Crossref]    [Pubmed]   
5. Brunt EM and Tiniakos DG. Pathological features of NASH. Front Biosci. 2005; 10:1475-1484. [Pubmed]   
6. Wieckowska A and Feldstein AE. Diagnosis of nonalcoholic fatty liver disease: invasive versus noninvasive. Semin Liver Dis. 2008; 28:386–395. [DOI via Crossref]    [Pubmed]   
7. Acharya M. Clinical, biochemical and histological profile of patients with non alcoholic steathepatitis (NASH) from Northern India. Proceeding of first consensus meet on NAFLD. 2005; 86.
8. Clark JM. The epidemiology of nonalcoholic fatty liver disease in adults. J Clin Gastroenterol. 2006; 40:5-10.
9. Leite NC, Salles GF, Araujo AL, et al. Prevalence and associated factors of non-alcoholic fatty liver disease in patients with type-2 diabetes mellitus. Liver Int. 2009; 29(1):113-119. [DOI via Crossref]    [Pubmed]   
10. Lizardi-Cervera J, Laparra DI, Chávez-Tapia NC, et al. Prevalence of NAFLD and metabolic syndrome in asymtomatics subjects. Rev Gastroenterol Mex. 2006; 71(4):453-459. [Pubmed]   
11. Sathiaraj E, Chutke M, Reddy M Y, et al. A case-control study on nutritional risk factors in non-alcoholic fatty liver disease in Indian population. Eur J Clin Nutr. 2011; 65 (4):533-537. [DOI via Crossref]    [Pubmed]   
12. Bajaj S, Nigam P, Luthra A, et al. A case-control study on insulin resistance, metabolic co-variates & prediction score in non-alcoholic fatty liveSr disease. Indian J Med Res. 2009; 129(3):285-292. [Pubmed]   

How to Cite this Article
Pubmed Style

Abhijit Sen, Jitendra Kumar, Rajendra Prasad Misra, Muneer Uddin, P. C. Shukla. Lipid profile of patients having non-alcoholic fatty liver disease as per ultrasound findings in north Indian population: A retrospective observational study. J Med Allied Sci. 2013; 3(2): 59-62.

Web Style

Abhijit Sen, Jitendra Kumar, Rajendra Prasad Misra, Muneer Uddin, P. C. Shukla. Lipid profile of patients having non-alcoholic fatty liver disease as per ultrasound findings in north Indian population: A retrospective observational study. https://jmas.in/?mno=211119 [Access: January 12, 2023].

AMA (American Medical Association) Style

Abhijit Sen, Jitendra Kumar, Rajendra Prasad Misra, Muneer Uddin, P. C. Shukla. Lipid profile of patients having non-alcoholic fatty liver disease as per ultrasound findings in north Indian population: A retrospective observational study. J Med Allied Sci. 2013; 3(2): 59-62.


Vancouver/ICMJE Style

Abhijit Sen, Jitendra Kumar, Rajendra Prasad Misra, Muneer Uddin, P. C. Shukla. Lipid profile of patients having non-alcoholic fatty liver disease as per ultrasound findings in north Indian population: A retrospective observational study. J Med Allied Sci. (2013), [cited January 12, 2023]; 3(2): 59-62.


Harvard Style

Abhijit Sen, Jitendra Kumar, Rajendra Prasad Misra, Muneer Uddin, P. C. Shukla (2013) Lipid profile of patients having non-alcoholic fatty liver disease as per ultrasound findings in north Indian population: A retrospective observational study. J Med Allied Sci, 3 (2), 59-62.


Turabian Style

Abhijit Sen, Jitendra Kumar, Rajendra Prasad Misra, Muneer Uddin, P. C. Shukla. 2013. Lipid profile of patients having non-alcoholic fatty liver disease as per ultrasound findings in north Indian population: A retrospective observational study. Journal of Medical and Allied Sciences, 3 (2), 59-62.


Chicago Style

Abhijit Sen, Jitendra Kumar, Rajendra Prasad Misra, Muneer Uddin, P. C. Shukla. "Lipid profile of patients having non-alcoholic fatty liver disease as per ultrasound findings in north Indian population: A retrospective observational study." Journal of Medical and Allied Sciences 3 (2013), 59-62.


MLA (The Modern Language Association) Style

Abhijit Sen, Jitendra Kumar, Rajendra Prasad Misra, Muneer Uddin, P. C. Shukla. "Lipid profile of patients having non-alcoholic fatty liver disease as per ultrasound findings in north Indian population: A retrospective observational study." Journal of Medical and Allied Sciences 3.2 (2013), 59-62. Print.


APA (American Psychological Association) Style

Abhijit Sen, Jitendra Kumar, Rajendra Prasad Misra, Muneer Uddin, P. C. Shukla (2013) Lipid profile of patients having non-alcoholic fatty liver disease as per ultrasound findings in north Indian population: A retrospective observational study. Journal of Medical and Allied Sciences, 3 (2), 59-62.


Author LoginReviewer LoginAbout PublisherPeer Review PolicyEditorial & Peer Review ProcessConflict of Interest PolicyAdvertising PolicyLicense InformationCopyright Information
Copyright © 2023 Journal of Medical and Allied Sciences All Rights Reserved. Subject to change without notice from or liability to Journal of Medical and Allied Sciences.
For best results, please use Internet Explorer or Google Chrome

Contact Information


By regular mail/speed post/courier

Dr. Nazia Uzma
Editor, JMAS,
Deccan College of Medical Sciences,
DMRL ‘X’ Road, Kanchanbagh (PO),
Hyderabad-500 058, Telangana, India.

By email: editorialoffice@jmas.in

By phone: +91 40 24340225, 24340129

By fax: +91 40 24340235